Description
CD57 antibody [NK-1] marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Studies have shown that CD57 expression is present in normal and neoplastic pituitaries. It has been reported that CD57 reactivity may be used as an additional immunophenotypic criterion in distinguishing nodular lymphocyte predominance Hodgkin’s disease from nodular sclerosing Hodgkin’s disease, T-cell-rich B-cell lymphoma, and follicular lymphoma. CD57 [NK-1] also reportedly stains neuroendocrine cells and their respective tumors.
SPECIFICATIONS
Specifications
| WEIGHT | N/A |
|---|---|
| DIMENSIONS | N/A |
| INTENDED USE | IVD |
| SPECIES REACTIVITY | Human |
| SOURCE | Mouse Monoclonal |
| CLONE | NK-1 |
| ISOTYPE | IgM/kappa |
| ANTIGEN | CD57 |
| LOCALIZATION | Cell membrane in germinal centers of lymph nodes or tonsils |
| POSITIVE CONTROL | Single tonsil |
DATASHEETS & SDS
INTERNATIONAL
ONCORE PROTOCOL
| ANTIBODY | DOWNLOAD |
|---|---|
| Download Oncore Protocol |
REFERENCES
1. Sanno N, et al. J Neurooncol. 1997 Oct; 35(1):29-38. 2. Papadimitriou CS, et al. Leuk Lymphoma. 1995 Dec; 20(1-2):125-30. 3. Atochina OV, et al. Tsitologiia. 1994; 36(9-10):1006-11. 4. Liu XH, et al. Hinyokika Kiyo. 1993 May; 39(5):439-44. 5. Kamel OW, et al. Am J Pathol. 1993 Feb; 142(2):541-6. 6. Ghali VS, Jimenez EJ, Garcia RL. Hum Pathol. 1992 Jan; 23(1):21-5.
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