CD31 Rat Monoclonal Antibody

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Description

CD31 Rat Monoclonal Antibody (PECAM-1) mediates cell-to-cell adhesion and supports the idea that it may be involved in some of the interactive events taking place during thrombosis, wound healing, and angiogenesis. Studies have shown CD31 is of value in the study of benign and malignant vascular tumors. Reliable identification of endothelial cells is a prerequisite for understanding vascularity changes in many cardiovascular diseases and therapeutic interventions. This rat anti-mouse CD31 antibody is expressed in endothelial cells from a variety of mouse tissues and is weakly expressed in peripheral lymphoid cells and platelets.

SPECIFICATIONS

Specifications

WEIGHT N/A
DIMENSIONS N/A
INTENDED USE RUO
SPECIES REACTIVITY Mouse
SOURCE Rat Monoclonal
CLONE Mec13.3
ISOTYPE Rat IgG2ak
ANTIGEN CD31
LOCALIZATION Cell surface
POSITIVE CONTROL Kidney, lung and colon
REFERENCES

1. Albelda SM, et al. J Cell Biol. 1991 Sep; 114(5):1059-68.
2. Ismail JA, et al. Cardiovasc Pathol. 2003 Mar-Apr; 12(2):82-90.

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