Description
CD20 antibody [L26] reacts with a protein of a 30-33 kDa polypeptide present in B-cells. L26 has been shown to react with the majority of B-cells present in peripheral blood and lymphoid tissues. In normal lymphoid tissue, CD20 [L26] marks B-cells in germinal centers, particularly immunoblasts. This antibody has been shown to be a reliable pan B-cell marker. Studies also show CD20 [L26] marking diffuse large B-cell lymphomas. CD20 [L26] rarely marks T-cells.
SPECIFICATIONS
Specifications
| INTENDED USE | IVD |
|---|---|
| SPECIES REACTIVITY | Human |
| SOURCE | Mouse Monoclonal |
| CLONE | L26 |
| ISOTYPE | IgG2a/kappa |
| ANTIGEN | CD20 (B-cell) |
| LOCALIZATION | Cell surface |
| POSITIVE CONTROL | Tonsil or B-cell lymphoma |
DATASHEETS & SDS
| Download Data Sheet |
| Download RUO Data Sheet for International |
| Download SDS Sheet |
Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.
REFERENCES
1. Kitamura A, et al. Histopathology. 2005 Nov; 47(5):523-32.
2. Tao K, et al. Zhonghua Bing Li Xue Za Zhi. 2002 Apr; 31(2):112-5.
3. Chen CC, et al. Appl Immunohistochem Mol Morphol. 2000 Mar; 8(1):1-11.
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