Description
Ber-EP4 is present on the surface and the cytoplasm of all epithelial cells except the superficial layers of squamous epithelial, hepatocytes and parietal cells. It shows a broad spectrum of reactivity with human epithelial cells including simple epithelia and basal layers of stratified non-keratinized squamous epithelium and epidermis. It does not label mesothelial cells and rarely marks mesotheliomas and has been reported to distinguish between adenocarcinomas from pleural mesotheliomas. Studies also suggest it may be useful for differentiating basal cell carcinoma from other dermatological conditions.
SPECIFICATIONS
Specifications
| INTENDED USE | IVD |
|---|---|
| SOURCE | Mouse Monoclonal |
| SPECIES REACTIVITY | Human |
| CLONE | Ber-EP4 |
| ISOTYPE | IgG1 |
| ANTIGEN | Ber-EP4 |
| LOCALIZATION | Cytoplasm, cell membrane |
| POSITIVE CONTROL | : Colon and breast cancer |
| BY LETTER | B |
DATASHEETS & SDS
ONCORE PROTOCOL
| ANTIBODY | DOWNLOAD |
|---|---|
| Download Oncore Protocol |
REFERENCES
1. Ansai S, et al. J Dermatol. 2012 Aug; 39(8):688-92.
2. Saladi RN, et al. Int J Dermatol. 2004 Aug; 43(8):600-3.
3. Koss MN, et al. Ann Diagn Pathol. 1998 Apr; 2(2):93-102.
4. Ordóñez NG. Am J Clin Pathol. 1998 Jan; 109(1):85-9.
5. Jensen ML, Johansen P. Diagn Cytopathol. 1996 Jul; 15(1):33-6.
6. Sheibani K, et al. Am J Surg Pathol. 1991 Aug; 15(8):779-84.
7. Gaffey MJ, et al. Am J Surg Pathol. 1992 Jun; 16(6):593-9.
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